Recombinant Human Thrombospondin-1 Protein

Product Discontinued

Recombinant Human Thrombospondin-1 Protein Summary

• Description: Recombinant protein for Human Thrombospondin-1
  
  

  Source:Baculovirus (Sf9 insect cells)
  Amino Acid Sequence:(P07996)

• Preparation Method: Determined to be >98% pure by SDS-PAGE
• Source: Sf 9 (baculovirus)
• Protein/Peptide Type: Recombinant Protein
• Gene: THBS1
• Purity: >98%, by SDS-PAGE
• Endotoxin Note: <0.1 ng/ug

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 180 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from 20 mM sodium phosphate (pH 6.0), 300 mM NaCl, 0.1% BSA.
• Concentration: Lyoph
• Purity: >98%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute with water to 0.1 mg/ml.

Alternate Names for Recombinant Human Thrombospondin-1 Protein

• THBS
• THBS1
• THBS-1
• thrombospondin 1
• Thrombospondin1
• Thrombospondin-1
• thrombospondin-1p180
• TSP-1
• TSP1thrombospondin-1
• TSPTSP-1

Background

Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been used as a potential regulator of tumor growth and metastasis. TSP expression is highly regulated by different hormones and cytokines and is developmentally controlled. TSP stimulates the growth of Vascular smooth muscle cells and human foreskin fibroblasts, a combination of IFN-gamma and TNF-alpha inhibits TSP production in these cells. Recombinant Human Thrombospondin is glycosylated with N-linked sugars and produced using baculovirus vectors in insect cells. Human Thrombospondin is purified by proprietary chromatographic techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: THBS1