TGN46 Antibody

Product Discontinued

TGN46 Antibody Summary

• Immunogen: Antisera to TGN46 were raised by repeated immunisations of sheep with highly purified recombinant human TGN46.
• Marker: TGN Marker
• Specificity: This is specific for TGN46. TGN46 is a heavily glycosylated protein of around 110-120kDa.
• Clonality: Polyclonal
• Host: Sheep
• Gene: TGOLN2
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:200
  • Immunomicroscopy
  • Western Blot 1:500-1:1000
• Control:

  TGN38 Overexpression Lysate

Reactivity Notes

This antibody is reactive against human and primate. Not yet tested in other species. This is the smaller size, 10ug, and a larger size, 25ug, is available at product NB110-40767.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 1.0% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.1 mg/ml
• Purity: IgG purified

Alternate Names for TGN46 Antibody

• TGN 46
• TGN 48
• TGN 51
• TGN38 homolog
• TGN38
• TGN-38
• TGN46
• TGN-46
• TGN48
• TGN51
• TGOLN 2
• TGOLN2
• trans golgi network 38
• trans golgi network 46
• Trans Golgi network integral membrane protein 2 [Precursor]
• Trans Golgi network integral membrane protein 2
• Trans Golgi network protein (46 48 51kD isoforms)
• Trans golgi network protein 2
• Trans Golgi network protein TGN51
• Trans-Golgi network integral membrane protein 2
• Trans-Golgi network protein 2
• Trans-Golgi network protein TGN51
• TTGN 2
• TTGN2

Background

Sheep anti-human TGN46 recognises a glycoprotein designated TGN46 that is localised primarily in the Trans-Golgi network. TGN46 has been reported as being the best available marker for human trans-Golgi network

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TGN46 Antibody (NB110-62093)(1)

Publication using NB110-62093

• Cha JH, Yang WH, Xia W et al. Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1 Mol. Cell 2018-08-16 [PMID: 30118680] (ICC/IF, Human)

Bioinformatics

• Gene Symbol: TGOLN2
• Entrez:
  • 10618(Human)