Western Blot: TGF-beta RII Antibody [NB100-91994] - Analysis of TGF BETA Receptor II (I122) pAb in extracts from HepG2 cells(65K) or LOVO cells(100K).
Western Blot: TGF-beta RII Antibody [NB100-91994] - Analysis of TGF-beta RII (I122) pAb at 1:500 dilution Lane1:Hela whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate
Simple Western: TGF-beta RII Antibody [NB100-91994] - Simple Western lane views show a specific band for TGF-beta RII (116 kDa) in mouse Ba/F3 (haematopoietic) cells. Image submitted by Dr. Ron Blance at The University ...read more
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS, pH 7.2.
0.05% Sodium Azide
Immunogen affinity purified
Western Blot 1:500-1:1000
Western blot (WB) analysis of TGF Beta Receptor II (I122) pAb in extracts from HepG2 cells(65K) or LOVO cells(100K). Immunocytochemistry/Immunofluorescence and Immunohistochemistry-Frozen were reported in scientific literature. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read 2 Reviews rated 4 using NB100-91994 in the following applications:
transforming growth factor, beta receptor II (70/80kDa) isoform 1
transforming growth factor, beta receptor II (70/80kDa) isoform 2
transforming growth factor, beta receptor II (70/80kDa)
transforming growth factor, beta receptor II (70-80kD)
Transforming growth factor-beta receptor type II
A total of three members of the TGFbeta family, TGFbeta1, TGFbeta2 and TGFbeta3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFbetas mediate their activity by high affinity binding to the type II receptor (TGFbeta RII) transmembrane protein with a cytoplasmic serine-threonine kinase domain. For signaling growth inhibition and early gene responses the type II receptor requires both its kinase activity and association with a TGFbeta-binding protein, designated the type I receptor. Two independent groups have recently described the cloning and sequence analysis of genes encoding TGFbeta type I receptor proteins designated ALK-5 (TbetaR-1) and TSR-1, respectively.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.