TFPI-2 Antibody

• Reactivity: Mu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

TFPI-2 Antibody Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse TFPI-2
  Leu23-Lys211
  Accession # O35536
• Specificity: Detects mouse TFPI-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross‑reactivity with recombiannt human (rh) TFPI-2, rhTFPI-1, and recombinant mouse TFPI-1 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: TFPI2
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 25 ug/mL
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for TFPI-2 Antibody

• Placental protein 5
• PP5
• PP5FLJ21164
• REF-1
• TFPI2
• TFPI-2
• TFPI-2REF1
• tissue factor pathway inhibitor 2

Background

TFPI-2 (tissue factor pathway inhibitor-2; also placental protein 5/PP5) is a secreted, presumably 27‑34 kDa glycoprotein member of the Kunitz domain-containing proteinase inhibitor family. In mouse, it is principally produced by endothelium, hepatocytes and synctiotrophoblasts, and serves as an inhibitor of multiple serine proteinases. Mature mouse TFPI-2 is 208 amino acids (aa) in length. It contains three Kunitz inhibitor domains, the most N-terminal of which (aa 36‑86) is crucial to inhibitor activity. Over aa 23‑211, mouse TFPI-2 shares 86% and 58% aa sequence identity with rat and human TFPI-2, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TFPI2
• Uniprot:
  • O35536()