TERF2IP Antibody (RAP1 5G7/1) [FITC]

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: RAP1 5G7/1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: FITC

TERF2IP Antibody (RAP1 5G7/1) [FITC] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Human TERF2IP
• Marker: Lysosome Marker
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TERF2IP
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB120-14403. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Alternate Names for TERF2IP Antibody (RAP1 5G7/1) [FITC]

• dopamine receptor interacting protein 5
• Dopamine receptor-interacting protein 5
• DRIP5
• hRap1
• RAP1 homolog
• RAP1TERF2-interacting telomeric protein 1
• Repressor/activator protein 1 homolog
• telomeric repeat binding factor 2, interacting protein
• telomeric repeat-binding factor 2-interacting protein 1
• TRF2-interacting telomeric protein 1
• TRF2-interacting telomeric RAP1 protein

Background

Mammalian telomeric proteins, including TRF1, TRF2, tankyrase, and TIN2 have no recognized orthologs in budding yeast. However, human Rap1 (hRap1) is an ortholog of the yeast telomeric protein, scRap1p. hRap1 is a homodimer, has three conserved sequence motifs in common with scRap1, is located at telomeres, and plays a role in telomere length regulation. Although scRap1 binds telomeric DNA directly, hRap1 is recruited to telomeres by TRF2 and binds it with its C-terminus, rather than directly binding DNA.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TERF2IP