TERF2IP Products

Description

Mammalian telomeric proteins, including TRF1, TRF2, tankyrase, and TIN2 have no recognized orthologs in budding yeast. However, human Rap1 (hRap1) is an ortholog of the yeast telomeric protein, scRap1p. hRap1 is a homodimer, has three conserved sequence motifs in common with scRap1, is located at telomeres, and plays a role in telomere length regulation. Although scRap1 binds telomeric DNA directly, hRap1 is recruited to telomeres by TRF2 and binds it with its C-terminus, rather than directly binding DNA.

Bioinformatics

Entrez	307861 Rat 54386 Human 57321 Mouse
Uniprot	NM_018975 Human NP_061848.2 Human Q9NYB0 Human
Product By Gene ID	54386
Alternate Names	dopamine receptor interacting protein 5 Dopamine receptor-interacting protein 5 DRIP5 hRap1 RAP1 homolog RAP1TERF2-interacting telomeric protein 1 Repressor/activator protein 1 homolog telomeric repeat binding factor 2, interacting protein telomeric repeat-binding factor 2-interacting protein 1 TRF2-interacting telomeric protein 1 TRF2-interacting telomeric RAP1 protein

Research Areas for TERF2IP

Find related products by research area and learn more about each of the different research areas below.

Cellular Markers
Chromatin Research
DNA Repair
Endosome Markers
Lysosome Markers