Species: Hu
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Ma
Applications: WB, ICC/IF, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Mammalian telomeric proteins, including TRF1, TRF2, tankyrase, and TIN2 have no recognized orthologs in budding yeast. However, human Rap1 (hRap1) is an ortholog of the yeast telomeric protein, scRap1p. hRap1 is a homodimer, has three conserved sequence motifs in common with scRap1, is located at telomeres, and plays a role in telomere length regulation. Although scRap1 binds telomeric DNA directly, hRap1 is recruited to telomeres by TRF2 and binds it with its C-terminus, rather than directly binding DNA.
Bioinformatics
| Entrez |
Rat
Human
Mouse
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
54386 |
| Alternate Names |
- dopamine receptor interacting protein 5
- Dopamine receptor-interacting protein 5
- DRIP5
- hRap1
- RAP1 homolog
- RAP1TERF2-interacting telomeric protein 1
- Repressor/activator protein 1 homolog
- telomeric repeat binding factor 2, interacting protein
- telomeric repeat-binding factor 2-interacting protein 1
- TRF2-interacting telomeric protein 1
- TRF2-interacting telomeric RAP1 protein
|
