TDP1 Antibody (2A10-G2)

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Sandwich ELISA: TDP1 Antibody (2A10-G2) [H00055775-M01] - Detection limit for recombinant GST tagged TDP1 is approximately 0.1ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
2A10-G2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

TDP1 Antibody (2A10-G2) Summary

Immunogen
TDP1 (AAH15474, 1 a.a. ~ 609 a.a) full length recombinant protein with GST tag.MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPNDGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGVKPKYNSGALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHAQAKPYENISLCQAKL
Specificity
TDP1 - tyrosyl-DNA phosphodiesterase 1
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TDP1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Publications
Read Publication using H00055775-M01.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TDP1 Antibody (2A10-G2)

  • EC 3.1.4
  • EC 3.1.4.-
  • FLJ11090
  • MGC104252
  • SCAN1
  • Tyr-DNA phosphodiesterase 1
  • tyrosyl-DNA phosphodiesterase 1

Background

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TDP1 Antibody (H00055775-M01)(1)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TDP1
Entrez
OMIM
Uniprot