TDP1 Products

Antibodies
TDP1 Antibody
TDP1 Antibody
NB100-81642
Species: Hu, Primate
Applications: WB, IHC, IHC-P, IP, PLA
Host: Rabbit Polyclonal
TDP1 Antibody
TDP1 Antibody
H00055775-D01P
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
TDP1 Antibody
TDP1 Antibody
NBP1-74175
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
Antibody Pairs
TDP1 Antibody Pair
TDP1 Antibody Pair
H00055775-PW1
Species: Hu
Applications: WB, IP
TDP1 Antibody Pair
TDP1 Antibody Pair
H00055775-AP11
Species: Hu
Applications: S-ELISA
Lysates
TDP1 Overexpression Lysate (D ...
TDP1 Overexpression Lysate (Denatu...
H00055775-T01
Species: Hu
Applications: WB
TDP1 Overexpression Lysate (N ...
TDP1 Overexpression Lysate (Native)
NBP2-08797
Applications: WB
TDP1 Overexpression Lysate (N ...
TDP1 Overexpression Lysate (Native)
NBL1-16800
Applications: WB
Proteins
TDP1 Recombinant Protein
TDP1 Recombinant Protein
NBP2-22912
Species: Hu
Applications: PAGE
RNAi
TDP1 RNAi
TDP1 RNAi
H00055775-R01
Species: Hu
TDP1 RNAi
TDP1 RNAi
H00055775-R02
Species: Hu

Description

TDP1 is encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 55775
Alternate Names
  • SCAN1
  • EC 3.1.4
  • Tyr-DNA phosphodiesterase 1
  • EC 3.1.4.-
  • FLJ11090
  • MGC104252
  • tyrosyl-DNA phosphodiesterase 1

Research Areas for TDP1

Find related products by research area and learn more about each of the different research areas below.

Stem Cell Markers

PTMs for TDP1

Learn more about PTMs related to TDP1.

Cleavage
Phosphorylation
Sumoylation
Phosphorothioation
Oxidation
Ubiquitination

Bioinformatics Tool for TDP1

Discover related pathways, diseases and genes to TDP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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