TCAP Antibody (OTI11H10) [mFluor Violet 500 SE]

• Reactivity: Hu, Mu
• Applications: WB, IHC
• Clone: OTI11H10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 500 SE

TCAP Antibody (OTI11H10) [mFluor Violet 500 SE] Summary

• Immunogen: Full length human recombinant protein of human TCAP (NP_003664) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TCAP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TCAP Antibody (OTI11H10) [mFluor Violet 500 SE]

• 19 kDa sarcomeric protein
• CMD1NTitin cap protein
• LGMD2G
• limb girdle muscular dystrophy 2G (autosomal recessive)
• T-cap
• TELE
• telethonin
• titin-cap (telethonin)

Background

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TCAP