TBLR1 Antibody (3G7) - Azide and BSA Free

Western Blot: TBLR1 Antibody (3G7) [H00079718-M01] - TBL1XR1 monoclonal antibody (M01), clone 3G7 Analysis of TBL1XR1 expression in HeLa.

Immunocytochemistry/Immunofluorescence: TBLR1 Antibody (3G7) [H00079718-M01] - Analysis of monoclonal antibody to TBL1XR1 on HeLa cell. Antibody concentration 10 ug/ml.

Immunohistochemistry-Paraffin: TBLR1 Antibody (3G7) [H00079718-M01] - Analysis of monoclonal antibody to TBL1XR1 on formalin-fixed paraffin-embedded human cerebral cortex. Antibody concentration 3 ug/ml.

ELISA: TBLR1 Antibody (3G7) [H00079718-M01] - Detection limit for recombinant GST tagged TBL1XR1 is 0.03 ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC, IP
• Clone: 3G7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

TBLR1 Antibody (3G7) - Azide and BSA Free Summary

• Immunogen: TBL1XR1 (NP_071347, 81 a.a. ~ 178 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQQGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWN
• Specificity: TBL1XR1 - transducin (beta)-like 1X-linked receptor 1
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: TBL1XR1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunofluoresence, immunohistochemistry (paraffin), and ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for TBLR1 Antibody (3G7) - Azide and BSA Free

• C21
• DC42
• F-box-like/WD repeat-containing protein TBL1XR1
• FLJ12894
• IRA1Transducin beta-like 1X-related protein 1
• Nuclear receptor corepressor/HDAC3 complex subunit TBLR1
• nuclear receptor co-repressor/HDAC3 complex subunit
• TBLR1TBL1-related protein 1
• transducin (beta)-like 1 X-linked receptor 1
• transducin (beta)-like 1X-linked receptor 1

Background

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TBLR1 Antibody (H00079718-M01)(2)

Publications using H00079718-M01

• Leandro V, Matt T, Andrew Z et al. TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate. Cell. 2020-07-02 [PMID: 32619424]
• Keutgens A, Shostak K, Close P et al. The Repressing Function of the Oncoprotein BCL-3 Requires CtBP, while Its Polyubiquitination and Degradation Involve the E3 Ligase TBLR1. Mol Cell Biol 30(16):4006-21. 2010-08-01 [PMID: 20547759]

Bioinformatics

• Gene Symbol: TBL1XR1
• Entrez:
  • 79718(Human)
• Uniprot:
  • NP_078941.2(Human)