TAO Kinase 1 Antibody - BSA Free

Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody - BSA Free [NBP1-50166] - Analysis of anti-TAOK1 antibody with human brain, cortex at concentration 5 ug/ml.

Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody - BSA Free [NBP1-50166] - Analysis of anti-TAOK1 antibody with human brain, cortex at concentration 5 ug/ml.

• Reactivity: Hu, Mu, Rt, Po, Bt, Bv, Ca, Ch, Eq, Ha, Pm, Pm, Rb, Xp, Av, Ma-Op
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

TAO Kinase 1 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 17 amino acid peptide from C-Terminus of human TAO Kinase 1.
• Epitope: C-Terminus
• Specificity: Human TAO Kinase 1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Avian (100%), Opossum (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TAOK1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml
• Application Notes: IHC-P: Requires pretreatment with Proteinase K..

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Zebrafish (88%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for TAO Kinase 1 Antibody - BSA Free

• EC 2.7.11
• FLJ14314
• hKFC-B
• hTAOK1
• KIAA1361
• KIAA1361STE20-like kinase PSK2
• Kinase from chicken homolog B
• MAP3K16
• MAP3K16EC 2.7.11.1
• MARK Kinase
• MARKK
• MARKKmicrotubule affinity regulating kinase kinase
• PSK2
• PSK-2
• PSK2serine/threonine kinase TAO1
• serine/threonine-protein kinase TAO1
• TAO Kinase 1
• TAO1serine/threonine protein kinase TAO1 homolog
• TAOK1
• Thousand and one amino acid protein 1

Background

TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TAOK1
• Entrez:
  • 57551(Human)
• Uniprot:
  • Q7L7X3(Human)