TAO Kinase 1 Antibody

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Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody [NBP1-50166] - Analysis of anti-TAOK1 antibody with human brain, cortex at concentration 5 ug/ml.
Immunohistochemistry-Paraffin: TAO Kinase 1 Antibody [NBP1-50166] - Analysis of anti-TAOK1 antibody with human brain, cortex at concentration 5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bt, Bv, Ca, Ch, Eq, Ha, Mk, Pm, Rb, Xp, Op, TrSpecies Glossary
Applications ELISA, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

TAO Kinase 1 Antibody Summary

Immunogen
Synthetic 17 amino acid peptide from C-Terminus of human TAOK1.
Specificity
Human TAOK1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Turkey (100%), Opossum (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TAOK1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 1:100 - 1:2000
  • Immunohistochemistry-Paraffin 5 ug/ml
Application Notes
IHC-P: Requires pretreatment with Proteinase K.

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (100%), Panda (100%), Platypus (100%), Zebrafish (88%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TAO Kinase 1 Antibody

  • EC 2.7.11
  • FLJ14314
  • hKFC-B
  • KIAA1361STE20-like kinase PSK2
  • Kinase from chicken homolog B
  • MAP3K16EC 2.7.11.1
  • MARKKmicrotubule affinity regulating kinase kinase
  • PSK2serine/threonine kinase TAO1
  • serine/threonine-protein kinase TAO1
  • TAO kinase 1
  • TAO1serine/threonine protein kinase TAO1 homolog
  • Thousand and one amino acid protein 1

Background

TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol TAOK1
Entrez
Uniprot