TAO Kinase 1 Antibody (TAO1 1.2) - BSA Free

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Genetic Strategies: Western Blot: TAO Kinase 1 Antibody (TAO1 1.2) [NBP2-50324] - HeLa cells were transfected with Negative control siRNA (Neg) or TAO1 siRNAs to assess the extent of protein depletion

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, KD
Clone
TAO1 1.2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml
Validated by:
     

Genetic Strategies

   

Order Details

TAO Kinase 1 Antibody (TAO1 1.2) - BSA Free Summary

Description
Clone also known as TAO_1.2_VMD
Immunogen
His-tagged recombinant human TAO Kinase 1 (722-1001) generated in E.coli
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
TAOK1
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:500
  • Knockdown Validated
  • Western Blot 1:100 - 1:2000
Application Notes
Staining Pattern: Cellular Cortex. Positive control(s): Lysate from HeLa cell line.
Theoretical MW
120 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for TAO Kinase 1 Antibody (TAO1 1.2) - BSA Free

  • EC 2.7.11
  • FLJ14314
  • hKFC-B
  • hTAOK1
  • KIAA1361
  • KIAA1361STE20-like kinase PSK2
  • Kinase from chicken homolog B
  • MAP3K16
  • MAP3K16EC 2.7.11.1
  • MARK Kinase
  • MARKK
  • MARKKmicrotubule affinity regulating kinase kinase
  • PSK2
  • PSK-2
  • PSK2serine/threonine kinase TAO1
  • serine/threonine-protein kinase TAO1
  • TAO Kinase 1
  • TAO1serine/threonine protein kinase TAO1 homolog
  • TAOK1
  • Thousand and one amino acid protein 1

Background

TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TAO Kinase 1 Antibody (NBP2-50324) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TAOK1