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TAO Kinase 1 Antibody (TAO1 1.2) [Alexa Fluor® 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, KD
Clone
TAO1 1.2
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 350

Order Details

TAO Kinase 1 Antibody (TAO1 1.2) [Alexa Fluor® 350] Summary

Description
Clone also known as TAO_1.2_VMD
Immunogen
His-tagged recombinant human TAO Kinase 1 (722-1001) generated in E.coli
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
TAOK1
Purity
Protein A purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Knockdown Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TAO Kinase 1 Antibody (TAO1 1.2) [Alexa Fluor® 350]

  • EC 2.7.11
  • FLJ14314
  • hKFC-B
  • hTAOK1
  • KIAA1361
  • KIAA1361STE20-like kinase PSK2
  • Kinase from chicken homolog B
  • MAP3K16
  • MAP3K16EC 2.7.11.1
  • MARK Kinase
  • MARKK
  • MARKKmicrotubule affinity regulating kinase kinase
  • PSK2
  • PSK-2
  • PSK2serine/threonine kinase TAO1
  • serine/threonine-protein kinase TAO1
  • TAO Kinase 1
  • TAO1serine/threonine protein kinase TAO1 homolog
  • TAOK1
  • Thousand and one amino acid protein 1

Background

TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TAOK1