Western Blot: TADA3L Antibody [NBP1-90243] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).
Immunocytochemistry/ Immunofluorescence: TADA3L Antibody [NBP1-90243] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry: TADA3L Antibody [NBP1-90243] - PCAF,TADA3L, and PACS1 protein expression is reduced in human gastric tumor tissue. A tissue microarray (TMA) containing gastric tumor tissue (Tumor) and ...read more
Western Blot: TADA3L Antibody [NBP1-90243] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp
Immunohistochemistry-Paraffin: TADA3L Antibody [NBP1-90243] - Staining of human vagina shows strong nuclear positivity in squamous epithelial cells.
Reactivity reported in scientific literature (PMID: 23435261)
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS (pH 7.2) and 40% Glycerol
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for TADA3L Antibody
alteration/deficiency in activation 3
epididymis secretory sperm binding protein
transcriptional adapter 3
Transcriptional adapter 3-like
transcriptional adaptor 3
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated genetranscription by interacting functionally with the general transcription machinery bound at the basal promoter.Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, therebyrelieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activatoradaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumorsuppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least fouralternatively spliced variants have been found for this gene, but the full-length nature of some variants has not beendetermined. (provided by RefSeq)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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