TAB2 Antibody

Western Blot: TAB2 Antibody [NBP2-20553] - Sample (30 ug of whole cell lysate) A: NIH-3T3 7. 5% SDS PAGE gel, diluted at 1:500.

Product Discontinued

TAB2 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human TAB2. The exact sequence is proprietary.
• Localization: Membrane; Peripheral membrane protein; Cytoplasm; cytosol
• Predicted Species: Human (100%), Rat (92%), Monkey (99%), Bovine (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TAB2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 76 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Rhesus Monkey (99%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for TAB2 Antibody

• FLJ21885
• KIAA0733CHTD2
• MAP3K7IP2mitogen-activated protein kinase kinase kinase 7 interacting protein 2
• Mitogen-activated protein kinase kinase kinase 7-interacting protein 2
• TAB-2
• TAK1-binding protein 2
• TGF-beta activated kinase 1/MAP3K7 binding protein 2
• TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
• TGF-beta-activated kinase 1-binding protein 2

Background

The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: TAB2
• Uniprot:
  • Q9NYJ8(Human)