TAB2 Antibody [mFluor Violet 450 SE]

• Reactivity: Hu, Mu, Rt
• Applications: IP, WB (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 450 SE

TAB2 Antibody [mFluor Violet 450 SE] Summary

• Immunogen: The immunogen for this product maps to a region between residue 300 and 350 of human TAK1-Binding Protein 2 using the numbering given in entry NP_055908.1 (GeneID 23118).
• Predicted Species: Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TAB2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TAB2 Antibody [mFluor Violet 450 SE]

• FLJ21885
• KIAA0733CHTD2
• MAP3K7IP2mitogen-activated protein kinase kinase kinase 7 interacting protein 2
• Mitogen-activated protein kinase kinase kinase 7-interacting protein 2
• TAB-2
• TAK1-binding protein 2
• TGF-beta activated kinase 1/MAP3K7 binding protein 2
• TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
• TGF-beta-activated kinase 1-binding protein 2

Background

TAB2 is encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TAB2