Syntaxin-BP1 Antibody

Images

 
Western Blot: Syntaxin-BP1 Antibody [NB100-41370] - (0.1ug/ml) staining of Human Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: Syntaxin-BP1 Antibody [NB100-41370] - (5ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-P, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Syntaxin-BP1 Antibody Summary

Immunogen
Peptide with sequence C-SRVSFEDQAPTME corresponding to C-Terminus according to NP_003156.1.
Epitope
C-SRVSFEDQAPTME
Specificity
This antibody is expected to recognize isoform a (NP_003156.1).
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
STXBP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 - 0.3 ug/ml
  • Immunohistochemistry 5 - 10 ug/ml
  • Immunohistochemistry-Paraffin 5 - 10 ug/ml
  • Peptide ELISA Detection limit 1:16000
Application Notes
WB: Approx. 75 kDa band observed in human and mouse brain lysates (calculated MW of 68.7 kDa band according to NP_003156.1). IHC-P: Human brain cortex shows vesicular staining in neuronal bodies.
Publications
Read Publication using NB100-41370.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Syntaxin-BP1 Antibody

  • EIEE4
  • FLJ37475
  • hUNC18
  • MUNC18-1
  • NSEC1
  • N-Sec1
  • p67
  • Protein unc-18 homolog 1
  • Protein unc-18 homolog A
  • rbSec1
  • STXBP1
  • syntaxin binding protein 1
  • syntaxin-binding protein 1
  • SyntaxinBP1
  • Syntaxin-BP1
  • UNC18
  • unc18-1
  • UNC18A
  • unc-18A
  • UNC18neuronal SEC1

Background

Munc18 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. It is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Munc18 can interact with syntaxins 1, 2, and 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Syntaxin-BP1 Antibody (NB100-41370)(1)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol STXBP1
Entrez
Uniprot