SUR1 Antibody

Images

 
Immunohistochemistry: SUR1 Antibody [19600002] - Most normal tissues exhibited moderate to strong cytoplasmic expression. Membranous staining pattern was seen in the intestinal tissues. Strong cytoplasmic ...read more
Immunohistochemistry: SUR1 Antibody [19600002] - Strong membranous staining pattern observed in colo-rectal cancers by immunohistochemistry. Image is provided courtesy of the Swedish Human Proteome Resource (HPR) ...read more
Immunohistochemistry: SUR1 Antibody [19600002] - IHC using anti ABCC8 SEQer antibody
ELISA: SUR1 Antibody [19600002]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

SUR1 Antibody Summary

Immunogen
This antibody is specific for the Middle Region of the target protein.
Specificity
This product is specific for Human SUR1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ABCC8
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This antibody is useful in ELISA and Immunohistochemistry-Paraffin.
Publications
Read Publications using 19600002.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for SUR1 Antibody

  • ABC36
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 8
  • HHF1Sulfonylurea receptor 1
  • HI
  • PHHIHRINS
  • sulfonylurea receptor (hyperinsulinemia)
  • SUR1MRP8
  • SURATP-binding cassette transporter sub-family C member 8
  • TNDM2ATP-binding cassette sub-family C member 8

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not been fully described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SUR1 Antibody (19600002)(2)

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Secondary Antibodies

 

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Bioinformatics Tool for SUR1 Antibody (19600002)

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Diseases for SUR1 Antibody (19600002)

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol ABCC8
Uniprot