SUR1 Products

Antibodies
SUR1 Antibody
SUR1 Antibody
19600002
Species: Hu
Applications: ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
SUR1 Antibody
SUR1 Antibody
NBP1-00138
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
SUR1 Antibody
SUR1 Antibody
NBP1-59778
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
SUR1 Partial Recombinant Prot ...
SUR1 Partial Recombinant Protein
H00006833-Q01
Species: Hu
Applications: WB, ELISA, PA
SUR1 Recombinant Protein Anti ...
SUR1 Recombinant Protein Antigen
NBP2-34077PEP
Species: Hu
Applications: AC
RNAi
SUR1 RNAi
SUR1 RNAi
H00006833-R02
Species: Hu

Description

SUR1 is encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not been fully described.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 6833
Alternate Names
  • sulfonylurea receptor (hyperinsulinemia)
  • ABC36
  • SURATP-binding cassette transporter sub-family C member 8
  • TNDM2ATP-binding cassette sub-family C member 8
  • PHHIHRINS
  • HHF1Sulfonylurea receptor 1
  • SUR1MRP8
  • HI
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 8

Research Areas for SUR1

Find related products by research area and learn more about each of the different research areas below.

ABC Transporters
Lipid and Metabolism
Nutrient Sensing in the Brain

PTMs for SUR1

Learn more about PTMs related to SUR1.

Methylation
Glycosylation
Demethylation
Carboxylation
Phosphorothioation
Oxidation

Bioinformatics Tool for SUR1

Discover related pathways, diseases and genes to SUR1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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