Substance P Parameter Assay Kit

Images

 

Product Details

Summary
Reactivity All-MultiSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price

Substance P Parameter Assay Kit Summary

Background
The Parameter Substance P Immunoassay is a 3.5 hour competitive enzyme immunoassay designed to measure Substance P in cell culture supernates, serum, plasma, saliva, and urine. It contains a synthetically derived human Substance P peptide and has been shown to accurately quantitate this peptide. Results obtained using samples containing natural Substance P showed linear curves that were para...llel to the standard curves obtained using the Parameter kit standards. These results indicate that this kit can be used to determine relative mass values for natural Substance P.
Show More
Specificity
Measures Substance P levels in various samples
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using KGE007.

Packaging, Storage & Formulations

Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Substance P Parameter Assay Kit

  • neurokinin 1
  • neurokinin 2
  • neurokinin A
  • Neurokinin-1
  • neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
  • neuropeptide gamma
  • neuropeptide K
  • NK2
  • NKA
  • NKNAneurokinin alpha
  • NPK
  • PPT
  • protachykinin-1
  • substance K
  • Substance P
  • TAC1
  • TAC2neuromedin L
  • tachykinin 2
  • tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2
  • tachykinin, precursor 1

Background

Substance P (SP, Neurokinin-1), is member of the Tachykinin peptide family and binds primarily to the Neurokinin 1 Receptor (NK1R, Substance P receptor, Tachykinin receptor 1) and with low affinity to the NK2 and NK3 receptors. Substance P is processed from preproTachykinin a, b, g and d isoforms that also generate other Tachykinins Neuropeptide K, Neurokinin A, Neurokinin B, and Neuropeptide G. Substance P is produced in the central nervous system, primary sensory neurons (C-type fibers), and endocrine cells of the intestinal mucosa. It triggers pain signals in the spinal cord dorsal horn as well as hypotension, tachycardia, release of inflammatory mediators, and direct antimicrobial action.

Customers Who Viewed This Item Also Viewed...

NBP1-05163
Species: Hu, Rt, Po, Bv
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NB120-14817
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, S-ELISA
NBP1-46535
Species: Hu, Mu, Rt, Rb, Xp, Ze
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IHC-FrFl
AF1052
Species: Hu
Applications: WB, Flow, IHC, CyTOF-ready
NBP2-37447
Species: Hu
Applications: WB, ELISA, Flow, IHC, IHC-P, CyTOF-ready, IF
NBP1-78982
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P
NB300-201
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
AF3899
Species: Mu
Applications: Flow, CyTOF-ready, ICC
NBP1-89993
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-33903
Species: Hu
Applications: IHC, IHC-P
NB300-201
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
NBP2-62664
Species: Hu
Applications: IHC, IHC-P
NB100-1533
Species: Hu, Mu, Rt, Po, Sh
Applications: WB, Flow, ICC/IF, IHC, IHC-P, PEP-ELISA
NB300-119
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
NBP2-67717
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NB300-109
Species: Hu, Mu, Rt, Dr, I, Ma
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P, Dual ISH-IHC, IHC-FrFl, IHC-WhMt, KO
KGE007
Species: All-Multi
Applications: ELISA
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Substance P (KGE007)(25)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Bovine.


Filter By Application
All Applications
Filter By Species
Human
(8)
Mouse
(12)
Rat
(4)
Bovine
(1)
All Species
Showing Publications 1 - 10 of 25. Show All 25 Publications.
Publications using KGE007 Applications Species
HK Lee, KW Kim, JS Ryu, HJ Jeong, SM Lee, MK Kim Bilateral Effect of the Unilateral Corneal Nerve Cut on Both Ocular Surface and Lacrimal Gland Invest. Ophthalmol. Vis. Sci., 2019;60(1):430-441. 2019 [PMID: 30703211] (Mouse) Mouse
Q Li, X Wu, Y Yang, Y Zhang, F He, X Xu, Z Zhang, L Tao, C Luo Tachykinin NK1 receptor antagonist L-733,060 and substance P deletion exert neuroprotection through inhibiting oxidative stress and cell death after traumatic brain injury in mice Int. J. Biochem. Cell Biol., 2018;0(0):. 2018 [PMID: 30593954] (Mouse) Mouse
Y Xu, C Huang, H Deng, J Jia, Y Wu, J Yang, W Tu TRPA1 and substance P mediate stress induced duodenal lesions in water immersion restraint stress rat model Turk J Gastroenterol, 2018;29(6):692-700. 2018 [PMID: 30381276] (Mouse) Mouse
Li Z, Luo T, Ning X, Xiong C, Wu A Neurokinin-1 receptor antagonism improves postoperative neurocognitive disorder in mice. Neurosci Lett, 0;687(0):189-195. 0 [PMID: 30273701] (Mouse) Mouse
DSC Butler, I Ambite, K Nagy, C Cafaro, A Ahmed, A Nadeem, N Filenko, TH Tran, KE Andersson, B Wullt, M Puthia, C Svanborg Neuroepithelial control of mucosal inflammation in acute cystitis Sci Rep, 2018;8(1):11015. 2018 [PMID: 30030504] (Mouse) Mouse
L Lorente, MM Martín, A Pérez-Ceja, J Ferreres, J Solé-Violá, L Labarta, C Díaz, A Jiménez Sustained Low Serum Substance P Levels in Non-Surviving Septic Patients Int J Mol Sci, 2017;18(7):. 2017 [PMID: 28714876] (Human) Human
L Xiao, M Ding, A Fernandez, P Zhao, L Jin, X Li Curcumin alleviates lumbar radiculopathy by reducing neuroinflammation, oxidative stress and nociceptive factors Eur Cell Mater, 2017;33(0):279-293. 2017 [PMID: 28485773] (Mouse) Mouse
AJ Sandweiss, MI McIntosh, A Moutal, R Davidson-K, J Hu, AK Giri, T Yamamoto, VJ Hruby, R Khanna, TM Largent-Mi, TW Vanderah Genetic and pharmacological antagonism of NK1 receptor prevents opiate abuse potential Mol. Psychiatry, 2017;0(0):. 2017 [PMID: 28485408] (Rat) Rat
Y Okamura, S Mishima, JI Kashiwakur, T Sasaki-Sak, S Toyoshima, K Kuroda, S Saito, Y Tokuhashi, Y Okayama The dual regulation of substance P-mediated inflammation via human synovial mast cells in rheumatoid arthritis Allergol Int, 2017;0(0):. 2017 [PMID: 28366675] (Human) Human
JA Singh, S Noorbalooc, KL Knutson Cytokine and neuropeptide levels are associated with pain relief in patients with chronically painful total knee arthroplasty: a pilot study BMC Musculoskelet Disord, 2017;18(1):17. 2017 [PMID: 28088207] (Human) Human
Show All 25 Publications.

Reviews for Substance P (KGE007) (0)

There are no reviews for Substance P (KGE007). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Substance P (KGE007). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.
Coronavirus Brochure

Customers Who Bought This Also Bought

NK1R Antibody
NB300-119

Contact Information

Product PDFs

Review this Product

Be the first to review our Substance P Parameter Assay Kit and receive a gift card or discount.