Home » STAT6 » STAT6 Antibodies » STAT6 [p Tyr641] Antibody (1248D) [Alexa Fluor® 750]

STAT6 [p Tyr641] Antibody (1248D) [Alexa Fluor® 750]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
1248D
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 750

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC3717U-100UG
Alexa Fluor 405
IC3717V-100UG
Alexa Fluor 488
IC3717G-100UG
Alexa Fluor 594
IC3717T-100UG
Alexa Fluor 647
IC37173R-025
Alexa Fluor 700
IC3717N-100UG
Phycoerythrin
IC37173P-025
Unconjugated
MAB3717
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3717
Carrier Free
MAB3717
Carrier Free
MAB3717-SP
Carrier Free
IC37173R-025
Carrier Free
IC37173P-025
Carrier Free
IC3717V-100UG
Carrier Free
IC3717U-100UG
Carrier Free
IC3717T-100UG
Carrier Free
IC3717G-100UG
Carrier Free
IC3717N-100UG
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STAT6 [p Tyr641] Antibody (1248D) [Alexa Fluor® 750] Summary

Immunogen
Phosphopeptide containing human STAT6 Y641 site.
Accession # P42226
Modification
p Tyr641
Specificity
Detects human STAT6 when phosphorylated at Y641.
Source
N/A
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for STAT6 [p Tyr641] Antibody (1248D) [Alexa Fluor® 750]

  • D12S1644
  • EC 2.4.1.227
  • EC 2.7.7.6
  • IL-4 Stat
  • IL-4-STAT
  • signal transducer and activator of transcription 6
  • signal transducer and activator of transcription 6, interleukin-4 induced
  • STAT, interleukin-4 induced
  • STAT, interleukin4-induced
  • STAT6
  • STAT6B
  • STAT6C
  • transcription factor IL-4 STAT

Background

Signal Transducer and Activator of Transcription 6 (STAT6) mediates the signaling of cytokines such as IL-4 and IL-13. STAT6 acts as a signal transducer in the cytoplasm and, upon phosphorylation at Y641, translocates to the nucleus and binds to the DNA consensus site TTCN4GAA. Knockout studies in mice suggest that STAT6 functions in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 IC3717U
Alexa Fluor 405 IC3717V
Alexa Fluor 488 IC3717G
Alexa Fluor 594 IC3717T
Alexa Fluor 647 IC37173R
Alexa Fluor 700 IC3717N
Alexa Fluor 750 IC3717S
Phycoerythrin IC37173P
Learn about Custom Antibody Labeling

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Blogs on STAT6.

Check out the latest blog posts on STAT6.
Signal Transducer and Activator of Transcription STAT6: More than a Player in Allergic Inflammation
By Jamshed Arslan, Pharm. D., PhD. What is STAT6?The cellular pathway comprising tyrosine kinase Janus Kinase (JAK) and the transcription factor STAT connect extracellular signals from various cytokines, hormones an...  Read full blog post.
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