SPRY2 Antibody

Western Blot: SPRY2 Antibody [H00010253-D01P] - Analysis of SPRY2 expression in HeLa.

Western Blot: SPRY2 Antibody [H00010253-D01P] - Analysis of SPRY2 expression in transfected 293T cell line by SPRY2 polyclonal antibody.Lane 1: SPRY2 transfected lysate(34.70 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

SPRY2 Antibody Summary

• Immunogen: SPRY2 (NP_005833.1, 1 a.a. - 315 a.a.) full-length human protein. MEARAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTRTSTSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKPGELKPLSKEDLGLHAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVCCKVPTVPPRNFEKPT
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SPRY2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is useful for Western Blot, Functional

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SPRY2 Antibody

• hSPRY2
• MGC23039
• protein sprouty homolog 2
• sprouty (Drosophila) homolog 2
• sprouty 2
• sprouty homolog 2 (Drosophila)
• SPRY2
• spry-2

Background

Sprouty 2 encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SPRY2
• Uniprot:
  • NP_005833.1(Human)