SPARC-like 1/SPARCL1 Antibody [mFluor Violet 500 SE]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: mFluor Violet 500 SE

SPARC-like 1/SPARCL1 Antibody [mFluor Violet 500 SE] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse SPARC-like 1/SPARCL1 (R&D Systems, Catalog # 4547-SL)
  Ile17-Phe650
  Accession # P70663
• Specificity: Detects mouse SPARC-like 1 in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross‑reactivity with recombinant human SPARC-like 1 is observed and less than 1% cross-reactivity with recombinant mouse SPARC is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SPARCL1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SPARC-like 1/SPARCL1 Antibody [mFluor Violet 500 SE]

• Hevin
• High endothelial venule protein
• MAST 9
• MAST9
• PIG33
• proliferation-inducing protein 33
• SC1
• SPARC like 1
• SPARCL1
• SPARC-like 1 (hevin)
• SPARC-like 1 (mast9, hevin)
• SPARC-like 1
• SPARC-like protein 1

Background

Human SPARC-like 1 (SPARCL1), also known as MAST9 or Hevin, is a member of the SPARC protein family. It is a secreted acidic calcium-binding protein of 664 amino acids that shows 62% identity with SPARC. SPARCL1 is a secreted protein, found in the extracellular matrix. It is expressed at high levels in high endothelial venules (HEV) in lymphoid tissues. SPARCL1 inactivation is a common event in tumors of epithelial origin and levels are down-regulated in a variety of tumors. It may have tumor suppressor activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SPARCL1