SP110 Antibody (OTI4C1) [HRP]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: OTI4C1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: HRP

SP110 Antibody (OTI4C1) [HRP] Summary

• Immunogen: Recombinant protein fragment corresponding to amino acids 232-521 of human SP110 (NP_004501) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SP110
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for SP110 Antibody (OTI4C1) [HRP]

• FLJ22835
• IFI41
• IFI75
• interferon-induced protein 41, 30kD
• Interferon-induced protein 41/75
• interferon-induced protein 75, 52kD
• IPR1
• phosphoprotein 41
• phosphoprotein 75
• SP110 nuclear body protein
• Speckled 110 kDa
• Transcriptional coactivator Sp110
• VODI

Background

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SP110