SOX5 Antibody [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 350

SOX5 Antibody [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant human SOX5
  Met417-Asn763
  Accession # P35711
• Specificity: Detects endogenous human SOX5 in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SOX5 Antibody [Alexa Fluor® 350]

• L-SOX5
• MGC35153
• SOX5
• SRY (sex determining region Y)-box 5
• transcription factor SOX-5

Background

SOX5 (SRY-related HMG box) is a 75-80 kDa Group D member of the SOX family of DNA-binding proteins. It is expressed in fetal chondrocytes and skeletal muscle, with a short form appearing in spermatids. SOX5 form homodimers and heterodimerizes with SOX6. Human SOX5 is 763 amino acids (aa) in length and contains two coiled-coil regions (aa 193-274 and 448-515), plus one Q/glutamine (aa 234-272) and one HMG box (aa 556-624). HMG domains participate in DNA-binding and protein-protein interaction. There are two alternate start sites at Met14 and Met417 (which creates a short/testis form), plus one variant with a three aa substitution for aa 389-763, another variant with a two aa substitution for aa 1-388, and a third variant with a one aa substitution for aa 534-763. Over aa 417-763, human SOX5 is 97% aa identical to mouse SOX5.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • P35711()