SOX1 Antibody

Product Discontinued

SOX1 Antibody Summary

• Immunogen: 196 RAVHMkEYPDYkYRPRRk 213
• Marker: Ectoderm Marker
• Specificity: The amino acidsequence used as immunogen shares significant homology with SOX1, 2, 3, 7, 11, 12, 14, 15, 20, and 21.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SOX1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:100-1:2000

Reactivity Notes

Dog,Human,New World monkey,Mouse,Opossum,Rat,Xenopus

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 ml PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SOX1 Antibody

• SOX1
• SRY (sex determining region Y)-box 1
• SRY-related HMG-box gene 1
• transcription factor SOX-1

Background

SOX3 is a SOX (SRY-related HMG-box) protein that shows its homology with SRY, the testis-determining gene. The homology is restricted to the region of SRY that encodes a DNA-binding motif of the HMG-box class (the DNA-binding domain is called HMG for 'high mobility group'). The SOX gene is located on the X chromosomeThis gene is highly conserverd and shows 97.2% similarity to the protein encoded by the mouse SOX3 gene. Along with SOX1 and SOX2, SOX3 coexpresses in self-renewing progenitor cells and act to inhibit neuronal differentiation. Active repression of the SOX genes promotes neural progenitor cells to initiate differentiation prematurely. It helps in pituitary development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SOX1