Somatostatin R5/SSTR5 Antibody

Images

 
Western Blot: Somatostatin R5/SSTR5 Antibody [NB100-74540] - Analysis of SSTR5 in human pituitary gland.
Flow Cytometry: Somatostatin R5/SSTR5 Antibody [NB100-74540] - Analysis of Somatostatin Receptor 5 was done on HT-29 cells.

Product Details

Summary
Reactivity Hu, Mu, PoSpecies Glossary
Applications WB, Flow, IHC, IHC-P, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
This product is unpurified. The exact concentration of antibody is not quantifiable.

Order Details

Somatostatin R5/SSTR5 Antibody Summary

Immunogen
Synthetic peptide corresponding to residues Q(344) E A T R P A H R A A A N G L M Q T S K L(364) of human SSTR5.
Specificity
Somatostatin Receptor 5
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SSTR5
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:4000 - 1:6000
  • Flow Cytometry 3 - 5 ug / 10^6 cells
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:2500
  • Immunocytochemistry 1:5000
Publications
Read Publications using
NB100-74540 in the following applications:

  • WB
    1 publication

Reactivity Notes

Porcine reactivity reported in scientific literature (PMID:33002813)

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Whole serum
Preservative
0.05% Sodium Azide
Concentration
This product is unpurified. The exact concentration of antibody is not quantifiable.
Purity
Unpurified

Alternate Names for Somatostatin R5/SSTR5 Antibody

  • Somatostatin R5
  • somatostatin receptor 5
  • somatostatin receptor subtype 5
  • somatostatin receptor type 5
  • SomatostatinR5
  • SS5R
  • SS-5-R
  • SS5-R
  • SST5
  • SSTR5

Background

Somatostatin Receptor Type 5 (SSTR5) has been reported to be expressed in adrenal, aorta, brain, breast, eye, heart, pancreas, prostate, skeletal muscle, small intestine, and thyroid. ESTs have been isolated from cartilage libraries. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This "turn-off" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates. Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Somatostatin R5/SSTR5 Antibody (NB100-74540)(2)

We have publications tested in 2 confirmed species: Mouse, Porcine.

We have publications tested in 1 application: WB.


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(1)
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Bioinformatics

Gene Symbol SSTR5
Entrez
Uniprot