Sodium Potassium ATPase Alpha 1 Antibody (464.6) [HRP]

• Reactivity: Hu, Mu, Rt, Po, Bv, Ca, Dr, Gp, Pm, Rb, Sh, Xp, Ye
• Applications: WB, Flow, ICC/IF, IHC, IP
• Clone: 464.6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: HRP

Sodium Potassium ATPase Alpha 1 Antibody (464.6) [HRP] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Purified Sodium Potassium ATPase Alpha 1 from rabbit renal outer medulla. [UniProt# Q9N0Z6]
• Specificity: This is specific for Na,K-ATPase alpha 1 subunit.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ATP1A1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP2-61137. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein G purified

Alternate Names for Sodium Potassium ATPase Alpha 1 Antibody (464.6) [HRP]

• ATP1A1
• ATPase, Na+/K+ transporting, alpha 1 polypeptide
• EC 3.6.3
• EC 3.6.3.9
• EC 7.2.2.13
• K-ATPase alpha-1 subunit
• K-ATPase catalytic subunit alpha-A protein
• MGC3285
• MGC51750
• Na
• Na(+)/K(+) ATPase alpha-1 subunit
• Na, K-ATPase, alpha-A catalytic polypeptide
• Na+, K+ ATPase alpha subunit
• Na+/K+ ATPase 1
• Sodium Potassium ATPase Alpha 1
• sodium pump 1
• Sodium pump subunit alpha-1
• sodium/potassium-transporting ATPase subunit alpha-1
• sodium-potassium-ATPase, alpha 1 polypeptide

Background

Sodium Potassium ATPase is an integral membrane protein complex that hydrolyzes ATP to maintain the transmembrane gradients of Na+ and K+ found in most mammalian cells. The Sodium Potassium ATPase enzyme is comprised of an alpha and beta subunit. The alpha-polypeptide (Sodium Potassium ATPase Alpha 1) has been shown to be the catalytically active subunit, whereas the Beta-polypeptide appears to be necessary for the assembly and transport of the sodium pump to the plasma membrane. Sodium Potassium ATPase alpha-1 subunit, in the brain, is expressed in both neuronal and non-neuronal cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Sodium Potassium ATPase Alpha 1 Antibody (NBP2-61137H)(2)

Publications using NBP2-61137H

• Christian Staehr, Palle Duun Rohde, Nikolaj Thure Krarup, Steffen Ringgaard, Christoffer Laustsen, Jacob Johnsen, Rikke Nielsen, Hans Christian Beck, Jens Preben Morth, Karin Lykke‐Hartmann, Nichlas Riise Jespersen, Denis Abramochkin, Mette Nyegaard, Hans Erik Bøtker, Christian Aalkjaer, Vladimir Matchkov Migraine‐Associated Mutation in the Na,K‐ATPase Leads to Disturbances in Cardiac Metabolism and Reduced Cardiac Function Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease 2022-03-15 [PMID: 35289188] (Western Blot, Rat)
• Kravtsova VV, Paramonova II, Vilchinskaya NA et al. Chronic Ouabain Prevents Na,K-ATPase Dysfunction and Targets AMPK and IL-6 in Disused Rat Soleus Muscle Int J Mol Sci 2021-04-30 [PMID: 33920198] (WB, Rat)
  
  Details:
  Citation using the HRP format of this antibody.

FAQs for Sodium Potassium ATPase Alpha 1 Antibody (NBP2-61137H). (Showing 1 - 1 of 1 FAQs).

1. I am looking forward to pick up a plasma membrane marker. I have gastric cancer cell line and I am preparing PM out of that. To just check the quality of prep, I need a plasma membrane marker.
   • Our sodium potassium ATPase and plasma membrane products may be of use to you. Please contact us at technical@novusbio.com with any additional questions.

Bioinformatics

• Gene Symbol: ATP1A1