SOCS-2 Antibody

ELISA: SOCS-2 Antibody [29920002]

Product Discontinued

SOCS-2 Antibody Summary

• Immunogen: This antibody is specific for the N Terminus Region of the target protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SOCS2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Potassium Phosphate (pH 7.0), 0.15 M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for SOCS-2 Antibody

• CIS2
• CIS2CIS-2
• Cish2
• Cytokine-inducible SH2 protein 2
• SOCS2
• SOCS-2
• SOCS-2STAT-induced STAT inhibitor 2
• SSI2
• SSI-2STAT induced STAT inhibitor-2
• SSI2STAT-induced STAT inhibitor-2
• STATI2
• STATI2suppressor of cytokine signaling-2
• suppressor of cytokine signaling 2

Background

The SOCS2 (suppressor of cytokine signaling-2) protein is a 23 kD cytoplasmic protein that contains a SOCS box and an SH2 domain. SOCS2 has been shown to be involved in postnatal growth hormone signaling, IGF-1 signaling via the JAK/STAT pathway, and neuronal differentiation. SOCS2 is induced by erythropoietin, GM-CSF, IL-10, and IFN- gamma. SOCS2 has been shown to interact with the IGF-1 and growth hormone receptors. The Poly6153 antibody recognizes the N-terminal region of human SOCS2 and has been shown to be useful for Western blotting.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SOCS-2 Antibody (29920002)(2)

Publications using 29920002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Bioinformatics

• Gene Symbol: SOCS2
• Entrez:
  • 8835(Human)
• Uniprot:
  • O14508()