SNAP23 Antibody

Western Blot: SNAP23 Antibody [H00008773-D01P] - Analysis of SNAP23 expression in transfected 293T cell line by SNAP23 polyclonal antibody.Lane 1: SNAP23 transfected lysate(23.40 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

SNAP23 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: SNAP23 (NP_003816.2, 1 a.a. - 211 a.a.) full-length human protein. MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETEKTLTELNKCCGLCVCPCNRTKNFESGKAYKTTWGDGGENSPCNVVSKQPGPVTNGQLQQPTTGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQIKRITDKADTNRDRIDIANARAKKLIDS
• Specificity: Reacts with synaptosomal-associated protein, 23kDa.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SNAP23
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SNAP23 Antibody

• HsT17016
• SNAP23
• SNAP-23
• SNAP23A
• SNAP23B
• synaptosomal-associated protein 23
• synaptosomal-associated protein, 23kD
• synaptosomal-associated protein, 23kDa
• Vesicle-membrane fusion protein SNAP-23

Background

Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SNAP23
• Entrez:
  • 8773(Human)
• Uniprot:
  • NP_003816.2(Human)