SNAP23 Products

Description

Synaptosomal-associated proteins (SNAPs) are cytosolic proteins that play a key role in in the process of membrane fusion in intracellular vesicle trafficking. In eukaryotic cells, the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex is critical to membrane docking and fusion and is believed to impart some degree of specificity between vesicle SNARE (v-SNARE) and target organelle SNARE (t-SNARE). In neurons and neuroendocrine cells, the SNARE complex consists of the integral membrane proteins VAMP (vesicle-associated membrane protein), syntaxin and SNAP-25. In non-neuronal tissue, a SNAP-25 homolog, SNAP-23, functionally replaces SNAP-25 in the SNARE complex. Studies show that VAMP, syntaxin and SNAP-23 are required for SNARE function and that this complex exists as a heterotrimer of the three proteins. In insulin signalling pathways, studies suggest that the translocation of GLUT4 in adipocytes requires that functional SNAP-23 be present in SNARE complexes.

Bioinformatics

Entrez	20619 Mouse 64630 Rat 8773 Human
Uniprot	AAH00148 Human NM_003825 Human NP_003816.2 Human O00161 Human
Product By Gene ID	8773
Alternate Names	HsT17016 SNAP-23 SNAP23A SNAP23B synaptosomal-associated protein 23 synaptosomal-associated protein, 23kD synaptosomal-associated protein, 23kDa Vesicle-membrane fusion protein SNAP-23

Research Areas for SNAP23

Find related products by research area and learn more about each of the different research areas below.

Membrane Trafficking and Chaperones
Neuronal Cell Markers
Neuroscience
Neurotransmission
Protein Phosphatase