SmarcAL1 Antibody

Western Blot: SmarcAL1 Antibody [NB100-81640] - Detection of Human SMARCAL1 on HeLa whole cell lysate using NB100-81640. SMARCAL1 was also immunoprecipitated by another rabbit anti-SMARCAL1 antibody.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

SmarcAL1 Antibody Summary

• Description: Novus Biologicals Rabbit SmarcAL1 Antibody (NB100-81640) is a polyclonal antibody validated for use in WB and IP. Anti-SmarcAL1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 904 and 954 of human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a-like 1 using the numbering given in entry NP_054859.2 (GeneID 50485).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SMARCAL1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:10-1:500
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SmarcAL1 Antibody

• ATP-driven annealing helicase
• EC 3.6.1
• EC 3.6.4.-
• HARPSWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A-like protein 1
• HepA-related protein
• HHARP
• SIOD
• SMARCA-like protein 1
• subfamily a-like 1
• Sucrose nonfermenting protein 2-like 1
• SWI/SNF related, matrix associated, actin dependent regulator of chromatin

Background

The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SmarcAL1 Antibody (NB100-81640)(1)

Publication using NB100-81640

• Yuan J, Ghosal G, Chen J et al. The annealing helicase HARP protects stalled replication forks. Genes Dev 2009-10-01 [PMID: 19793864]

Bioinformatics

• Gene Symbol: SMARCAL1
• Entrez:
  • 50485(Human)
• Uniprot:
  • NP_054859.2(Human)