Smad7 Antibody - Azide and BSA Free

Immunohistochemistry-Paraffin: Smad7 Antibody [NBP2-98971] - Immunochemical staining of human Smad7 in human liver with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).

Immunohistochemistry-Paraffin: Smad7 Antibody [NBP2-98971] - Immunochemical staining of human Smad7 in human hepatoma with rabbit polyclonal antibody (1:500, formalin-fixed paraffin embedded sections).

Product Discontinued

Smad7 Antibody - Azide and BSA Free Summary

• Description: This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human Smad7.
• Predicted Species: Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SMAD7
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1:250-1:1000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Antigen and protein A Affinity-purified

Alternate Names for Smad7 Antibody - Azide and BSA Free

• CRCS3
• FLJ16482
• hSMAD7
• MAD homolog 7
• MAD homolog 8
• MAD, mothers against decapentaplegic homolog 7 (Drosophila)
• MADH7
• MADH7mothers against decapentaplegic homolog 7
• MADH8
• Mothers against decapentaplegic homolog 8
• Mothers against decapentaplegic, drosophila, homolog of, 7
• Mothers against DPP homolog 7
• Mothers against DPP homolog 8
• SMAD 7
• SMAD family member 7MAD (mothers against decapentaplegic, Drosophila) homolog 7
• SMAD, mothers against DPP homolog 7 (Drosophila)
• SMAD, mothers against DPP homolog 7
• Smad7

Background

SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily (1). SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD5, SMAD8 and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8 and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used asalternate namesfor one another in the literature. Human SMAD1 is a 465 amino acid protein; GenBank Accession No. AAP36050.1. Human SMAD2 is a 467 amino acid protein; GenBank Accession No. AAC51918.1 Human SMAD3 is a 425 amino acid protein; GenBank Accession No. NP_005893.1 Human SMAD4 is a 552 amino acid protein GenBank Accession No. NP_005350.1. Human SMAD5 is a 465 amino acid protein; GenBank Accession No. AAC50791.1. Human SMAD6 is a 496 amino acid protein; GenBank Accession No. AAH12986.1 Human SMAD7 is a 426 amino acid protein; GenBank Accession No. AAB81354.1 Mouse SMAD8 is a 430 amino acid protein; GenBank Accession No. AAN85445.1 Human SMAD9 is a 430 amino acid protein; GenBank Accession No. NP_005896.1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SMAD7