SLX4 Antibody (2392A) [Alexa Fluor® 594]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 2392A
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 594

SLX4 Antibody (2392A) [Alexa Fluor® 594] Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Synthetic peptide within amino acids 400-500 of the Human SLX4 protein sequence
• Specificity: Detects Human SLX4 immunogen sequences in Direct ELISA.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SLX4 Antibody (2392A) [Alexa Fluor® 594]

• BTB (POZ) domain containing 12
• BTB/POZ domain-containing protein 12
• BTBD12
• BTBD12structure-specific endonuclease subunit SLX4
• FANCP
• KIAA1784
• KIAA1784MUS312
• KIAA1987
• KIAA1987FANCP
• SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
• SLX4

Background

SLX4 (also known as BTBD12 and FANCP) is a multidomain scaffold protein involved in DNA repair, where it has important roles in the final steps of homologous recombination. SLX4 hat interacts with three distinct nucleases: SLX1, ERCC4/XPF-ERCC1 and MUS81-EME1. Mutations in the gene are associated with the disease Fanconi anemia, a rare recessive disorder characterized by genome instability, congenital malformations, progressive bone marrow failure and predisposition to hematologic malignancies and solid tumors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.