SLC7A9 Antibody

Product Discontinued

SLC7A9 Antibody Summary

• Immunogen: The immunogen for this antibody was a sequence from 3a.a. to 19a.a. from SLC7A9(a 487a.a. long protein)
• Localization: Cell membrane; cell-cell junction. Cell membrane; cell-matrix junction. Found at cell-cell boundaries and probably at cell-matrix boundaries.
• Specificity: SLC7A9
• Clonality: Polyclonal
• Host: Chicken
• Gene: SLC7A9
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA

Reactivity Notes

This antibody is reactive against Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for SLC7A9 Antibody

• b(0,+)AT
• b(0+)AT
• B(0+)-type amino acid transporter 1
• BAT1
• bo+ amino acid transporter
• CSNU3
• FLJ94301
• Glycoprotein-associated amino acid transporter b0+AT1
• SLC7A9
• solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
• Solute carrier family 7 member 9

Background

SLC7A9 belongs to the amino acid-polyamine-organocation (APC) superfamily. It is a disulfide linked heterodimer with the amino acid transport protein SLC3A1. SLC7A9 is involved in the high affinity, sodium independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high affinity reabsorption of cystine in the kidney tubule. Defects in SLC7A9 are a cause of non type I cystinuria (CSNU). CSNU arises from impaired transport of cystine and dibasic amino acids through the epithelial cells of the renal tubule and gastrointestinal tract. Three types of cystinuria have been described: type I (fully recessive or silent); type II (high excretor); type III (moderate excretor). Defects in SLC7A9 are associated with type II and type III cystinuria. They also might account for some non classic type I cystinuria cases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC7A9
• Entrez:
  • 11136(Human)
• Uniprot:
  • P82251(Human)