SLC5A5/Sodium Iodide Symporter Antibody (FP5) [Alexa Fluor® 488]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF, IHC, MA
• Clone: FP5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

SLC5A5/Sodium Iodide Symporter Antibody (FP5) [Alexa Fluor® 488] Summary

• Immunogen: Mannose binding protein hNIS fusion (AA468-643)
• Localization: Membrane
• Specificity: Detects approx 97kDa, non-glycosylated version at 68kDa. Other minor bands associated with hNIS at 160kDa, and degradation products at approx 30 kDa, and approx 15kDa.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: SLC5A5
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Microarray
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SLC5A5/Sodium Iodide Symporter Antibody (FP5) [Alexa Fluor® 488]

• Na(+)/I(-) cotransporter
• Na(+)/I(-) symporter
• NIS
• NISNa(+)/I(-)-symporter
• SLC5A5
• sodium/iodide cotransporter
• Sodium-iodide symporter
• solute carrier family 5 (sodium iodide symporter), member 5
• Solute carrier family 5 member 5
• TDH1

Background

The Sodium Iodide Symporter gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the meta

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SLC5A5/Sodium Iodide Symporter Antibody (NBP1-70342AF488)(1)

Publication using NBP1-70342AF488

• Oh JM, Rajendran RL, Gangadaran P Et al. Targeting GLI1 Transcription Factor for Restoring Iodine Avidity with Redifferentiation in Radioactive-Iodine Refractory Thyroid Cancers Cancers (Basel) 2022-04-12 [PMID: 35406554] (WB, ICC/IF, Mouse, Human)
  
  Details:
  Citation using the Alexa Fluor 488 version of this antibody.

Bioinformatics

• Gene Symbol: SLC5A5
• Entrez:
  • 65199(Rat)
• Uniprot:
  • W9JM47(Rat)