SLC39A14 Antibody - BSA Free

Western Blot: SLC39A14 Antibody [NBP1-76510] - Human spleen tissue lysate with SLC9A14 antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry: SLC39A14 Antibody - BSA Free [NBP1-76510] - Immunohistochemistry of SLC39A14 in mouse liver tissue with SLC39A14 antibody at 2.5 u/mL.

Immunocytochemistry/ Immunofluorescence: SLC39A14 Antibody - BSA Free [NBP1-76510] - Immunofluorescence of SLC39A14 in Mouse Liver tissue with SLC39A14 antibody at 20 u/mL.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

SLC39A14 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit SLC39A14 Antibody - BSA Free (NBP1-76510) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. Anti-SLC39A14 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP14. The immunogen is located within amino acids 230 - 280 of ZIP14. Amino Acid Squence: KQKNEHHHGHSHYASE
• Specificity: At least three isoforms of ZIP14 are known to exist; this antibody will detect both isoforms. ZIP14 antibody is predicted to not cross-react with other ZIP family members.
• Predicted Species: Bovine (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SLC39A14
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1-2 ug/ml
• Theoretical MW: 52 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Control Peptide:

  SLC39A14 Peptide (NBP1-76510PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for SLC39A14 Antibody - BSA Free

• Irt-like protein 14
• LIV-1 subfamily of ZIP zinc transporter 4
• LZT-Hs4
• solute carrier family 39 (metal ion transporter), member 14
• solute carrier family 39 (zinc transporter), member 14
• solute carrier family 39 member 14
• zinc transporter ZIP14
• ZIP14
• ZIP-14
• zrt- and Irt-like protein 14

Background

The zinc transporter ZIP14, also known as SLC39A14, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP14 is a glycosylated multipass plasma membrane protein that belongs to the ZIP transporter subfamily LIV-1. ZIP14 has been shown to contribute to the hypozincemia of inflammation and infection and is regulated in the liver by IL-6. In addition to zinc, ZIP14 is also involved in the cellular uptake of non-transferrin-bound iron as well as iron bound to transferrin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SLC39A14 Antibody (NBP1-76510)(1)

Publication using NBP1-76510

• Brian S. Muntean, Subhi Marwari, Xiaona Li, Douglas C. Sloan, Brian D. Young, James A. Wohlschlegel, Kirill A. Martemyanov Members of the KCTD family are major regulators of cAMP signaling Proceedings of the National Academy of Sciences of the United States of America 2021-12-21 [PMID: 34934014]

FAQs for SLC39A14 Antibody (NBP1-76510). (Showing 1 - 1 of 1 FAQ).

1. What is the position of the epitope in the protein structure?
   • The immunogen for NBP1-76510 is within amino acids 241-300 of accession number NP_001128625.

Bioinformatics

• Gene Symbol: SLC39A14
• Uniprot:
  • NP_001128625(Human)