Sin1/MAPKAP1 Antibody Blocking Peptide

Product Discontinued

Sin1/MAPKAP1 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 19 amino acids near the amino terminus of human MAPKAP1.

  Source: Synthetic

  (Accession #: NP_001006618)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: MAPKAP1
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-76776.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for Sin1/MAPKAP1 Antibody Blocking Peptide

• JC310
• MAPKAP1
• MEKK2-interacting protein 1
• MGC2745
• MIP1
• MIP1SIN1SIN1b
• Mitogen-activated protein kinase 2-associated protein 1
• mitogen-activated protein kinase associated protein 1
• mSIN1
• ras inhibitor MGC2745
• SAPK-interacting protein 1
• Sin1
• SIN1g
• stress-activated map kinase interacting protein 1
• Stress-activated map kinase-interacting protein 1
• stress-activated protein kinase-interacting 1
• target of rapamycin complex 2 subunit MAPKAP1
• TORC2 subunit MAPKAP1

Background

Sin1 is a novel component of the eukaryotic SAPK pathway. Sin1 and the H3 and H4 histones interact genetically, with the C terminus of Sin1 physically associating with components of the SWI-SNF complex. This interaction is blocked by the N-terminal half of the protein in full length Sin1. It has been proposed that Sin1 acts as a regulatable bridge between the SWI-SNF complex and the nucleosome Sin1 is also required for effective transcription via the AP-1 factor Pap1, but does not prevent its nuclear translocation. Sin1 is a novel component of the eukaryotic SAPK pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: MAPKAP1