SIK1/Snf1lk Antibody - BSA Free

Western Blot: SIK1/Snf1lk Antibody [NBP1-76571] - Human small intestine tissue lysate with SIK1/Snf1lk antibody at 1 ug/mL.

Immunohistochemistry: SIK1/Snf1lk Antibody - BSA Free [NBP1-76571] - Immunohistochemistry of SIK1/Snf1lk in human small intestine tissue with SIK1/Snf1lk antibody at 5 ug/mL.

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

SIK1/Snf1lk Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit SIK1/Snf1lk Antibody - BSA Free (NBP1-76571) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against an 18 amino acid synthetic peptide near the center of human SIK1. The immunogen is located within amino acids 340 - 390 of SIK1. Amino Acid Squence: ARPGPARQPRPRSSDLS
• Specificity: Two isoforms of SIK1 are known to exist; this antibody will detect both isoforms. SIK1 antibody is predicted to not cross-react with other SIK protein family members.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SIK1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1 ug/ml
• Control Peptide:

  SIK1/Snf1lk Peptide (NBP1-76571PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for SIK1/Snf1lk Antibody - BSA Free

• EC 2.7.11
• EC 2.7.11.1
• msk
• myocardial SNF1-like kinase
• salt-inducible kinase 1
• Salt-inducible protein kinase 1
• serine/threonine protein kinase
• serine/threonine-protein kinase SIK1
• Serine/threonine-protein kinase SNF1-like kinase 1
• Serine/threonine-protein kinase SNF1LK
• SIK
• SIK1
• SIK-1
• SIK1/Snf1lk
• SNF1-like kinase
• SNF1LK
• SNF1LKMSK

Background

Salt-inducible kinase 1 (SIK1), also known as SNF1LK or MSK, plays a role in histone modification and G2/M cell cycle regulation. It is a 783 amino acid protein that contains one UBA domain and belongs to the Ser/Thr protein kinase family (AMPK subfamily). Localized to both the nucleus and the cytoplasm, SIK1 is a class II HDAC kinase that uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SIK1
• Uniprot:
  • NP_775490(Human)