Signal Peptide Peptidase Antibody [Alexa Fluor™ Plus 488]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 488

Signal Peptide Peptidase Antibody [Alexa Fluor™ Plus 488] Summary

• Immunogen: The immunogen this antibody was made to, maps to a region between residue 327 to 377 of human Signal Peptide Peptidase Like 1 using the numbering given in entry NP_110416.1 (GeneID 81502).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HM13
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Signal Peptide Peptidase Antibody [Alexa Fluor™ Plus 488]

• dJ324O17.1
• EC 3.4.23.-
• H13hIMP1
• histocompatibility (minor) 13
• IMP-1
• IMP1MSTP086
• Intramembrane protease 1
• minor histocompatibility antigen 13
• minor histocompatibility antigen H13
• Presenilin-like protein 3
• PSENL3
• PSL3IMPAS
• signal peptide peptidase beta
• Signal peptide peptidase
• SPPIMPAS-1

Background

Signal Peptide Peptidase is encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HM13