Siglec-3/CD33 Antibody (C33/68) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, ICC/IF, IHC-Fr
Clone
C33/68
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

Siglec-3/CD33 Antibody (C33/68) [DyLight 405] Summary

Immunogen
Recombinant human CD33 protein
Localization
Cell surface
Specificity
Recognizes a 67kDa glycoprotein, which is identified as CD33. It is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CD33
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Siglec-3/CD33 Antibody (C33/68) [DyLight 405]

  • CD33 antigen (gp67)
  • CD33 antigen
  • CD33 molecule
  • CD33
  • FLJ00391
  • gp67
  • myeloid cell surface antigen CD33
  • p67
  • sialic acid binding Ig-like lectin 3
  • Sialic acid-binding Ig-like lectin 3
  • Siglec3
  • Siglec-3
  • SIGLEC3gp67

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Siglec-3/CD33 Antibody (NBP2-34579V) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34579AF350
Alexa Fluor 405 NBP2-34579AF405
Alexa Fluor 488 NBP2-34579AF488
Alexa Fluor 532 NBP2-34579AF532
Alexa Fluor 594 NBP2-34579AF594
Alexa Fluor 647 NBP2-34579AF647
Alexa Fluor 700 NBP2-34579AF700
Alexa Fluor 750 NBP2-34579AF750
Allophycocyanin NBP2-34579APC
Allophycocyanin/Cy7 NBP2-34579APCCY7
Biotin NBP2-34579B
DyLight 350 NBP2-34579UV
DyLight 405 NBP2-34579V
DyLight 488 NBP2-34579G
DyLight 550 NBP2-34579R
DyLight 650 NBP2-34579C
DyLight 680 NBP2-34579FR
DyLight 755 NBP2-34579IR
HRP NBP2-34579H
Janelia Fluor 549 NBP2-34579JF549
Janelia Fluor 646 NBP2-34579JF646
PE NBP2-34579PE
PE/Atto594 NBP2-34579PEATT594
PE/Cy5.5 NBP2-34579PECY55
PE/Cy7 NBP2-34579PECY7
PerCP NBP2-34579PCP

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Bioinformatics Tool for Siglec-3/CD33 Antibody (NBP2-34579V)

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Bioinformatics

Gene Symbol CD33