SHMT1 Antibody

Western Blot: SHMT1 Antibody [H00006470-D01P] - Analysis of SHMT1 expression in human liver.

Western Blot: SHMT1 Antibody [H00006470-D01P] - Analysis of SHMT1 expression in transfected 293T cell line by SHMT1 polyclonal antibody.Lane 1: SHMT1 transfected lysate(53.10 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

SHMT1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: SHMT1 (NP_004160.3, 1 a.a. - 483 a.a.) full-length human protein. MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGLPDF
• Specificity: SHMT1 - serine hydroxymethyltransferase 1 (soluble),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SHMT1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SHMT1 Antibody

• 14 kDa protein
• CSHMT
• cytoplasmic serine hydroxymethyltransferase
• EC 2.1.2.1
• Glycine hydroxymethyltransferase
• MGC15229
• MGC24556
• serine hydroxymethyltransferase 1 (soluble)
• serine hydroxymethyltransferase, cytosolic
• Serine methylase
• SHMT
• SHMT1
• SHMTEC 2.1.2.1

Background

This gene encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SHMT1
• Entrez:
  • 6470(Human)
• Uniprot:
  • NP_004160.3(Human)