SHMT1 Products

Antibodies
SHMT1 Antibody
SHMT1 Antibody
NBP2-32173
Species: Hu, Mu
Applications: WB, ELISA, IHC, IP
Host: Rabbit Polyclonal
SHMT1 Antibody
SHMT1 Antibody
NBP1-85437
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
SHMT1 Antibody (4F9)
SHMT1 Antibody (4F9)
H00006470-M01
Species: Hu
Applications: WB, ELISA, IHC-P
Host: Mouse Monoclonal
Lysates
SHMT1 Overexpression Lysate ( ...
SHMT1 Overexpression Lysate (Denat...
H00006470-T01
Species: Hu
Applications: WB
SHMT1 Overexpression Lysate ( ...
SHMT1 Overexpression Lysate (Native)
NBL1-15947
Applications: WB
SHMT1 Overexpression Lysate ( ...
SHMT1 Overexpression Lysate (Native)
NBL1-15946
Applications: WB
Proteins
SHMT1 Recombinant Protein Ant ...
SHMT1 Recombinant Protein Antigen
NBP1-85437PEP
Species: Hu
Applications: AC
Recombinant Human SHMT1 Prote ...
Recombinant Human SHMT1 Protein
NBP1-72548
Species: Hu
Applications: PAGE
RNAi
SHMT1 RNAi
SHMT1 RNAi
H00006470-R01
Species: Hu
Applications: RNAi, RNAi SP
SHMT1 RNAi
SHMT1 RNAi
H00006470-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

SHMT1 encodes the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing of this gene results in 2 transcript variants encoding 2 different isoforms. Additional transcript variants have been described, but their biological validity has not been determined.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 6470
Alternate Names
  • Glycine hydroxymethyltransferase
  • serine hydroxymethyltransferase, cytosolic
  • MGC24556
  • cytoplasmic serine hydroxymethyltransferase
  • MGC15229
  • 14 kDa protein
  • CSHMT
  • SHMTEC 2.1.2.1
  • Serine methylase
  • serine hydroxymethyltransferase 1 (soluble)

PTMs for SHMT1

Learn more about PTMs related to SHMT1.

Methylation
Sumoylation
Phosphorylation
Cleavage
Ubiquitination

Bioinformatics Tool for SHMT1

Discover related pathways, diseases and genes to SHMT1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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