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SH3BP5 Antibody [DyLight 594]

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Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP3-45363DL594
    • Availability
      Product Discontinued

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SH3BP5 Antibody [DyLight 594] Summary

Immunogen
SH3-domain binding protein 5(BTK-associated). (Uniprot# O60239)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SH3BP5
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SH3BP5 Antibody [DyLight 594]

  • Sab
  • SABSH3BP-5
  • SH3 binding protein
  • SH3 domain-binding protein 5
  • SH3 domain-binding protein that preferentially associates with BTK
  • SH3-domain binding protein 5 (BTK-associated)

Background

SH3BP5 (SH3 domain binding protein 5) binds to the SH3 domain of Bruton tyrosine kinase (BTK), a cytoplasmic tyrosine kinase crucial for the maturation of B-lineage cells. It inhibits the auto- and transphosphorylation activity of BTK and negatively regulates BTK-related cytoplasmic signaling in B-cells. SH3BP5 also interacts with JNK. The interaction with JNK occurs through a mitogen-activated protein KIM (kinase interaction motif) in a region distinct from the Bruton's tyrosine kinase-binding domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SH3BP5