SH3BP5 Products

Antibodies
SH3BP5 Antibody (2B3)
SH3BP5 Antibody (2B3)
H00009467-M01
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
Host: Mouse Monoclonal
SH3BP5 Antibody
SH3BP5 Antibody
NBP1-80796
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
SH3BP5 Antibody
SH3BP5 Antibody
NBP2-20343
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
SH3BP5 Overexpression Lysate ...
SH3BP5 Overexpression Lysate (Native)
NBP2-07817
Applications: WB
Proteins
Recombinant Human SH3BP5 Prot ...
Recombinant Human SH3BP5 Protein
H00009467-Q01
Species: Hu
Applications: WB, ELISA, PA
SH3BP5 Recombinant Protein An ...
SH3BP5 Recombinant Protein Antigen
NBP1-80796PEP
Species: Hu
Applications: AC
RNAi
SH3BP5 RNAi
SH3BP5 RNAi
H00009467-R01
Species: Hu
Applications: RNAi, RNAi SP
SH3BP5 RNAi
SH3BP5 RNAi
H00009467-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

SH3BP5 (SH3 domain binding protein 5) binds to the SH3 domain of Bruton tyrosine kinase (BTK), a cytoplasmic tyrosine kinase crucial for the maturation of B-lineage cells. It inhibits the auto- and transphosphorylation activity of BTK and negatively regulates BTK-related cytoplasmic signaling in B-cells. SH3BP5 also interacts with JNK. The interaction with JNK occurs through a mitogen-activated protein KIM (kinase interaction motif) in a region distinct from the Bruton's tyrosine kinase-binding domain.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 9467
Alternate Names
  • SH3 domain-binding protein 5
  • Sab
  • SH3 binding protein
  • SH3 domain-binding protein that preferentially associates with BTK
  • SABSH3BP-5
  • SH3-domain binding protein 5 (BTK-associated)

Pathways for SH3BP5

View related products by pathway and learn more about each of the pathways below.

Cell Death
Gene Silencing
Cell Cycle
Cell Development
Localization

PTMs for SH3BP5

Learn more about PTMs related to SH3BP5.

Phosphorylation

Bioinformatics Tool for SH3BP5

Discover related pathways, diseases and genes to SH3BP5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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