SGK1 Antibody

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Western Blot: SGK1 Antibody [NBP2-19010] - Analysis of SGK1 in human lung lysate in the 1) absence and 2) presence of immunizing peptide, 3) human kidney lysate probed with 1 ug/ml of SGK1 antibody. Goat anti-rabbit Ig ...read more
Immunohistochemistry-Paraffin: SGK1 Antibody [NBP2-19010] - analysis of SGK1 in human lung probed with SGK1 antibody at 5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Pm, Bv, Ca, Pm, Eq, Pm, Ma-Op, RM, ZeSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

SGK1 Antibody Summary

Immunogen
A portion of amino acids 360-410 from human SGK1 was used as the immunogen for this antibody. NP_005618.2.
Predicted Species
Mouse (90%), Rat (90%), Porcine (95%), Baboon (100%), Chimpanzee (100%), Bovine (95%), Zebrafish (95%), Rhesus Macaque (100%), Opossum (100%), Canine (95%), Equine (95%), Monkey (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SGK1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1-3 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 5 ug/ml
Publications
Read Publication using
NBP2-19010 in the following applications:

  • WB
    1 publication

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: 100% homologous in human, new world monkey, macaque, rhesus monkey, opossum, gibbon, orangutan, and chimpanzee; 95% in panda, carolina anole, cow, dog, chinese hamster, zebrafish, horse, mole rat, elephant, platypus, and pig; 90% in mouse, rat, zebra finch, frog, cichlid fish, rabbit, guinea pig, chicken, and wild turkey; 85% in salmon.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A purified

Alternate Names for SGK1 Antibody

  • EC 2.7.11
  • EC 2.7.11.1
  • serine/threonine protein kinase SGK
  • serine/threonine-protein kinase Sgk1
  • serum/glucocorticoid regulated kinase 1
  • serum/glucocorticoid regulated kinase
  • Serum/glucocorticoid-regulated kinase 1
  • SGK
  • SGK1

Background

SGK1, an acronym for serum and glucocorticoid regulated kinase, appears to be important for intrauterine embryo implantation and pregnancy maintenance along with a variety of other pathways such as neuronal excitation, renal sodium ion secretion, apoptosis and T-cell signaling. SGK1 activity and stability appears to have an inverse correlation with ubiquitinylation pathways. SGK1 has an interaction with Notch through Fbw as the absence of SGK1 promotes Notch protein stability and transcriptional activity. SGK1 association with Tcell signaling is also indicated as Notch and Fbw7 mutations are found in a majority of T-ALL cases. SGK1 antibodies can be useful for further analysis of the relative importance of this kinase in numerous diverse cell processes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SGK1 Antibody (NBP2-19010)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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Bioinformatics

Gene Symbol SGK1