SFRS8 Antibody [HRP]

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: HRP

SFRS8 Antibody [HRP] Summary

• Immunogen: splicing factor, arginine/serine-rich 8(suppressor-of-white-apricot homolog, Drosophila). (Uniprot# Q12872)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SFSWAP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for SFRS8 Antibody [HRP]

• Drosophila homolog)
• Drosophila)
• SFRS8
• splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog
• splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot
• Splicing factor, arginine/serine-rich 8
• splicing factor, suppressor of white-apricot homolog (Drosophila)
• splicing factor, suppressor of white-apricot homolog
• Suppressor of white apricot protein homolog
• SWAPMGC167082

Background

SFRS8 regulates the splicing of CD45, a protein which through alternative splice variants, has an essential role in activating T cells. T cells are involved in the pathogenesis of atopic diseases such as asthma, making SFRS8 a very interesting candidate gene in the region. SFRS8 could act as a weak predisposing gene for asthma. [from: http://www.ncbi.nlm.nih.gov/sites/entrez®cmd=Retrieve&db=PubMed&list_uids=16738036&dopt=Abstract] The basic functions of SFRS8 are the mediation of protein-protein interactions within the intron during spliceosome assembly, independently binding to exonic enhancer sequences, and recruiting components to adjacent introns for splice-site recognition and alternative splicing. [from: http://www.dsi.univ-paris5.fr/genatlas/fiche1.php®symbol=SFRS8]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SFSWAP