SFRS18 Antibody

Immunocytochemistry/Immunofluorescence: SFRS18 Antibody [NBP1-88723] - Staining of human cell line HeLa shows positivity in cytoplasm & nucleus but excluded from the nucleoli.

Immunohistochemistry-Paraffin: SFRS18 Antibody [NBP1-88723] - Staining of human kidney shows moderate cytoplasmic positivity in cells in tubules.

• Reactivity: Hu, Mu, Rt
• Applications: ICC/IF, IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

SFRS18 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: PLNQQQWMQSFQHQQDPSQIDWAALAQAWIAQREASGQQSMVEQPPGMMPNGQDMSTMESGPNNHGNFQGDSNFNRMWQPEWGMHQQPPHPPPDQPWMPPTPGPMDIVPPSEDSNSQDSGEFAPDNRHIFNQNNHNFGG
• Predicted Species: Mouse (97%), Rat (99%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PNISR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  SFRS18 Protein (NBP1-88723PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for SFRS18 Antibody

• bA98I9.2
• C6orf111
• chromosome 6 open reading frame 111
• DKFZp564B0769
• FLJ14752
• FLJ14992
• FLJ90147
• HSPC306
• MGC104269
• RP11-98I9.2
• Serine/arginine-rich-splicing regulatory protein 130
• serine-arginine-rich-splicing regulatory protein 130
• Splicing factor, arginine/serine-rich 130
• splicing factor, arginine/serine-rich 18
• SR rich protein
• SR-related protein
• SR-rich protein
• SRRP130
• SRrp130FLJ14853

Background

SFRS18/SRrp130 (splicing factor arginine/serine-rich 18) is a putative alternative splicing factor. It was identified as a factor that interacts with pinin (Pnn/DRS/memA), a cell-adhesion and nuclear protein of corneal epithelial cells. SFRS18/SRrp130 bears multiple arginine/serine-rich repeats found among the SR-related family of pre-mRNA processing factors. SFRS18/SRrp130 and pinin co-localize and are distributed as nuclear specks that correspond to the pre-splicing machinery.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PNISR