SETMAR Antibody

Western Blot: SETMAR Antibody [NB100-1142] - Analysis of SETMAR in Daudi lysate using this antibody at 2 ug/ ml. Primary incubated for 12 hour. Detected using chemiluminescence.

• Reactivity: Hu, Bv
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

SETMAR Antibody Summary

• Immunogen: Peptide with sequence RWQKCVDCNGSYFD corresponding to C-Terminus according to NP_006506.3.
• Predicted Species: Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SETMAR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:16000
  • Western Blot 1 - 3 ug/ml
• Application Notes: WB: Approx. 70-75 kDa band observed in Daudi lysate.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SETMAR Antibody

• EC 2.1.1.43
• histone-lysine N-methyltransferase SETMAR
• hsMar1
• METNASE
• SET domain and mariner transposase fusion gene
• SET domain and mariner transposase fusion gene-containing protein

Background

Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. Has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Has DNA nicking activity. Has in vivo end joining activity and may mediate genomic integration of foreign DNA

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SETMAR Antibody (NB100-1142)(4)

Publications using NB100-1142

• Anisha GS, Padmakumari S, Patel AK et Al. Fucoidan from Marine Macroalgae: Biological Actions and Applications in Regenerative Medicine, Drug Delivery Systems and Food Industry Bioengineering (Basel) 2022-09-14 [PMID: 36135017]
• Tan M, Jiang X. Norovirus Capsid Protein-Derived Nanoparticles and Polymers as Versatile Platforms for Antigen Presentation and Vaccine Development Pharmaceutics 2019-09-12 [PMID: 31547456]
• Alfonso NY, Alonge O, Hoque DME et al. Care-Seeking Patterns and Direct Economic Burden of Injuries in Bangladesh International Journal of Environmental Research and Public Health 2017-04-29 [PMID: 28468240]
• Robertson HM, Zumpano KL. Molecular evolution of an ancient mariner transposon, Hsmar1, in the human genome. Gene 1997-12-31 [PMID: 9461395]

Bioinformatics

• Gene Symbol: SETMAR
• Entrez:
  • 6419(Human)
• Uniprot:
  • NP_006506.(Human)