Serum Amyloid A1 Antibody (902738) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: IHC
• Clone: 902738
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

Serum Amyloid A1 Antibody (902738) [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant human Serum Amyloid A1
  Accession # P0DJI8
• Specificity: Detects human Serum Amyloid A1 in direct ELISAs.
• Isotype: IgG3
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Serum Amyloid A1 Antibody (902738) [Alexa Fluor® 350]

• MGC111216
• PIG4
• SAA
• SAA1
• SAA2
• serum amyloid A protein
• Serum Amyloid A1
• TP53I4
• tumor protein p53 inducible protein 4

Background

Human serum amyloid A protein-1 (SAA-1) is a multifunctional apolipoprotein produced by hepatocytes in response to proinflammatory cytokines.  It is secreted as a 12 kDa, 104 amino acid (aa), nonglycosylated polypeptide that displaces apoA1 in the HDL₃ complex (SwissProt #P02735).  The SAA-1 gene is one of three SAA genes in human, and it shows multiple alleles that are race dependent.  The SAA-1 gene product differs from the SAA-2 gene product by only seven amino acids.  Circulating SAA-1 shows multiple proteolytically-generated isoforms, with anywhere from one-to-three amino acids being cleaved from either the N- or C-terminus.  Mature human SAA-1 is 72%, 82% and 72% aa identical to mature mouse, rabbit and hamster SAA-1, respectively.   

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.